Natural sugar found in the popular sweetener reduces artery plaque by 30%
A natural sugar found in honey could prevent heart attacks, new research suggests.
The sugar, known as trehalose, activates a protein that causes immune cells to remove fatty plaque from arteries, the study found.
Trehalose was found to reduce the size of plaque in mice by around 30 percent.
Plaque builds up inside the arteries in a condition known as atherosclerosis. This causes the arteries to harden and become less elastic, putting people at risk of high blood pressure, heart disease and even heart attacks.
Trehalose is also found in mushrooms, lobsters and prawns.
How the study was carried out
Researchers from Washington University injected mice at risk of atherosclerosis with trehalose or a different type of sugar.
Some mice were also given trehalose orally.
Results, published in Nature Communications, revealed that mice given trehalose had plaques measuring 0.25mm across, compared with 0.35mm in the animals not injected with the sugar.
This is an approximate 30 percent decrease in plaque.
Plaque size was not reduced in mice given trehalose orally or those injected with a different type of sugar.
Trehalose is thought to activate a protein called TFEB that causes immune cells, known as macrophages, to remove plaque.
Lead author Dr Babak Razani said: ‘In atherosclerosis, macrophages try to fix damage to the artery by cleaning up the area, but they get overwhelmed by the inflammatory nature of the plaques.
‘Their housekeeping process gets gummed up.
‘Trehalose is not just enhancing the housekeeping machinery that’s already there. It’s triggering the cell to make new machinery.’
Written by Alexandra Thompson, Health Reporter for The Daily Mail ~ June 8, 2017.
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